PDBe 2m7p

Solution NMR

RXFP1 utilises hydrophobic moieties on a signalling surface of the LDLa module to mediate receptor activation

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Low-density lipoprotein receptor; Relaxin receptor 1 Chain: A
Molecule details ›
Chain: A
Length: 42 amino acids
Theoretical weight: 4.55 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9HBX9 (Residues: 25-25, 28-40; Coverage: 2%)
  • Canonical: P01130 (Residues: 67-68, 83-104; Coverage: 3%)
  • nullnull
Gene names: LDLR, LGR7, RXFP1
Structure domains: Low-density Lipoprotein Receptor

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 85%
Refinement method: torsion angle dynamics
Chemical shifts: BMR19200  
Expression system: Escherichia coli