PDBe 2m68

Solution NMR

NMR solution structure ensemble of 3-4D mutant domain 11 IGF2R in complex with IGF2 (domain 11 structure only)

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cation-independent mannose-6-phosphate receptor Chain: A
Molecule details ›
Chain: A
Length: 142 amino acids
Theoretical weight: 15.43 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: NEW P11717 (Residues: 1508-1649; Coverage: 6%)
Gene names: IGF2R, MPRI
Structure domains: Mannose-6-phosphate receptor binding domain

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 88%
Refinement method: DGSA-distance geometry simulated annealing
Chemical shifts: BMR19117  
Expression system: Escherichia coli