PDBe 2m5k


Atomic-resolution structure of a doublet cross-beta amyloid fibril


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
homo 912-mer (preferred)
homo octamer
Entry contents:
1 distinct polypeptide molecule
Transthyretin Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 11 amino acids
Theoretical weight: 1.2 KDa
Source organism: Rattus norvegicus
Expression system: Not provided
  • Canonical: P02767 (Residues: 125-135; Coverage: 9%)
Gene names: Tt, Ttr

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Experimental Method: Electron Microscopy, Solid-state NMR
Resolution: 12.7Å
Relevant EMDB volumes: EMD-5590
Expression system: Not provided