PDBe 2lzl

Solution NMR

Function and Biology Details

Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fibroblast growth factor receptor 3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 43 amino acids
Theoretical weight: 4.6 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P22607 (Residues: 357-399; Coverage: 6%)
Gene names: FGFR3, JTK4

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 47%
Refinement method: simulated annealing
Chemical shifts: BMR18763  
Expression system: Escherichia coli BL21(DE3)