PDBe 2lz4

Solution NMR

Solution NMR structure of transmembrane domain of amyloid precursor protein V44M

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
P3(42) Chains: A, B
Molecule details ›
Chains: A, B
Length: 31 amino acids
Theoretical weight: 3.18 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P05067 (Residues: 699-726; Coverage: 4%)
Gene names: A4, AD1, APP

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 47%
Refinement method: simulated annealing
Chemical shifts: BMR18648  
Expression system: Escherichia coli BL21(DE3)