PDBe 2lz1

Solution NMR

Solution NMR Structure of the DNA-Binding Domain of Human NF-E2-Related Factor 2, Northeast Structural Genomics Consortium (NESG) Target HR3520O

Released:
Source organism: Homo sapiens
Entry authors: Eletsky A, Pulavarti SVSRK, Lee D, Kohan E, Janjua H, Xiao R, Acton TB, Everett JK, Montelione GT, Szyperski T, Northeast Structural Genomics Consortium (NESG)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nuclear factor erythroid 2-related factor 2 Chain: A
Molecule details ›
Chain: A
Length: 90 amino acids
Theoretical weight: 10.67 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q16236 (Residues: 445-523; Coverage: 13%)
Gene names: NFE2L2, NRF2
Structure domains: Transcription factor, Skn-1-like, DNA-binding domain

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 88%
Refinement method: simulated annealing
Chemical shifts: BMR18735  
Expression system: Escherichia coli BL21(DE3)