PDBe 2lyw

Solution NMR

Intermolecular interactions between neurotensin and the third extracellular loop of human neurotensin 1 receptor

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Neurotensin receptor type 1 Chain: A
Molecule details ›
Chain: A
Length: 24 amino acids
Theoretical weight: 3.18 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P30989 (Residues: 321-344; Coverage: 6%)
Gene names: NTRR, NTSR1
Neurotensin Chain: B
Molecule details ›
Chain: B
Length: 13 amino acids
Theoretical weight: 1.68 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P30990 (Residues: 151-163; Coverage: 9%)
Gene name: NTS

Ligands and Environments

No bound ligands

1 modified residue:

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 48%
Refinement method: DGSA-distance geometry simulated annealing
Expression system: Not provided