PDBe 2lwz

Solution NMR

NMR Structures of Single-chain Insulin

Released:
Source organism: Homo sapiens
Entry authors: Weiss MA, Yang Y

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Insulin B chain Chain: A
Molecule details ›
Chain: A
Length: 57 amino acids
Theoretical weight: 6.38 KDa
Source organism: Homo sapiens
Expression system: Komagataella pastoris
UniProt:
  • Canonical: P01308 (Residues: 25-54, 89-110; Coverage: 61%)
Gene name: INS
Sequence domains: Insulin/IGF/Relaxin family
Structure domains: Insulin-like

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 83%
Refinement method: simulated annealing
Chemical shifts: BMR18654  
Expression system: Komagataella pastoris