PDBe 2loh

Solution NMR

Dimeric structure of transmembrane domain of amyloid precursor protein in micellar environment

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Amyloid-beta protein 42 Chains: A, B
Molecule details ›
Chains: A, B
Length: 43 amino acids
Theoretical weight: 4.45 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P05067 (Residues: 686-726; Coverage: 5%)
Gene names: A4, AD1, APP

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 44%
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)