PDBe 2lob

Solution NMR

PDZ Domain of CAL (Cystic Fibrosis Transmembrane Regulator-Associated Ligand)


Function and Biology Details

Biochemical function:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Golgi-associated PDZ and coiled-coil motif-containing protein Chain: A
Molecule details ›
Chain: A
Length: 112 amino acids
Theoretical weight: 12.53 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q9HD26 (Residues: 286-370; Coverage: 18%)
Gene names: CAL, FIG, GOPC
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain
Cystic fibrosis transmembrane conductance regulator Chain: B
Molecule details ›
Chain: B
Length: 8 amino acids
Theoretical weight: 990 Da
Source organism: Homo sapiens
Expression system: Not provided
  • Canonical: P13569 (Residues: 1473-1480; Coverage: 1%)
Gene names: ABCC7, CFTR

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 27%
Refinement method: DGSA-distance geometry simulated annealing
Chemical shifts: BMR18205  
Expression systems:
  • Escherichia coli
  • Not provided