PDBe 2lck

Solution NMR

Structure of the mitochondrial uncoupling protein 2 determined by NMR molecular fragment replacement

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mitochondrial uncoupling protein 2 Chain: A
Molecule details ›
Chain: A
Length: 303 amino acids
Theoretical weight: 33.06 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P70406 (Residues: 14-309; Coverage: 96%)
Gene names: Slc25a8, Ucp2
Sequence domains: Mitochondrial carrier protein
Structure domains: Mitochondrial carrier domain

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 34%
Refinement method: RDC-based Molecular Fragment Replacement, simulated annealing
Chemical shifts: BMR17614  
Expression system: Escherichia coli