PDBe 2l1c

Solution NMR

Shc-PTB:biphosphorylated integrin beta3 cytoplasmic tail complex (1:1)

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
SHC-transforming protein 1 Chain: A
Molecule details ›
Chain: A
Length: 211 amino acids
Theoretical weight: 23.17 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P29353 (Residues: 127-317; Coverage: 33%)
Gene names: SHC, SHC1, SHCA
Structure domains: Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Integrin beta-3 Chain: B
Molecule details ›
Chain: B
Length: 27 amino acids
Theoretical weight: 3.28 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P05106 (Residues: 762-788; Coverage: 4%)
Gene names: GP3A, ITGB3

Ligands and Environments

No bound ligands

1 modified residue:

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 80%
Refinement method: DGSA-distance geometry simulated annealing
Chemical shifts: BMR17080  
Expression systems:
  • Escherichia coli
  • Not provided