PDBe 2kvd

Solution NMR

Mesencephalic astrocyte-derived neurotrophic factor (MANF)


Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Mesencephalic astrocyte-derived neurotrophic factor Chain: A
Molecule details ›
Chain: A
Length: 160 amino acids
Theoretical weight: 18.34 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P55145 (Residues: 25-182; Coverage: 100%)
Gene names: ARMET, ARP, MANF
Sequence domains: Degradation arginine-rich protein for mis-folding
Structure domains:

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: TORSION ANGLE DYNAMICS, simulated annealing, TORSION ANGLE DYNAMICS
Expression system: Escherichia coli