PDBe 2k2d

Solution NMR

Solution NMR structure of C-terminal domain of human pirh2. Northeast Structural Genomics Consortium (NESG) target HT2C

Released:
Source organism: Homo sapiens

Function and Biology Details

Reaction catalysed:
S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
RING finger and CHY zinc finger domain-containing protein 1 Chain: A
Molecule details ›
Chain: A
Length: 79 amino acids
Theoretical weight: 9.04 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q96PM5 (Residues: 187-261; Coverage: 29%)
Gene names: ARNIP, CHIMP, PIRH2, RCHY1, RNF199, ZNF363
Sequence domains: Zinc-ribbon
Structure domains: Rubrerythrin, domain 2

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 90%
Refinement method: molecular dynamics
Chemical shifts: BMR15701  
Expression system: Escherichia coli BL21(DE3)