PDBe 2k18

Solution NMR

Solution structure of bb' domains of human protein disulfide isomerase

Released:

Function and Biology Details

Reaction catalysed:
Catalyzes the rearrangement of -S-S- bonds in proteins. 
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein disulfide-isomerase Chain: A
Molecule details ›
Chain: A
Length: 228 amino acids
Theoretical weight: 25.56 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P07237 (Residues: 135-357; Coverage: 45%)
Gene names: ERBA2L, P4HB, PDI, PDIA1, PO4DB
Sequence domains: Thioredoxin-like domain
Structure domains: Glutaredoxin

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli BL21