PDBe 2jqk

Solution NMR

VPS4B MIT-CHMP2B Complex

Released:
Source organism: Homo sapiens

Function and Biology Details

Reaction catalysed:
ATP + H(2)O = ADP + phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Charged multivesicular body protein 2b Chain: B
Molecule details ›
Chain: B
Length: 19 amino acids
Theoretical weight: 2.12 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9UQN3 (Residues: 195-213; Coverage: 9%)
Gene names: CGI-84, CHMP2B
Vacuolar protein sorting-associated protein 4B Chain: A
Molecule details ›
Chain: A
Length: 89 amino acids
Theoretical weight: 10.19 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O75351 (Residues: 1-86; Coverage: 19%)
Gene names: MIG1, SKD1, VPS42, VPS4B
Sequence domains: MIT (microtubule interacting and transport) domain
Structure domains: Hypothetical protein 1500032h18.

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)