PDBe 2jmu

Solution NMR

NMR structure of the mouse thiamine triphosphatase

Released:
Source organism: Mus musculus

Function and Biology Details

Reaction catalysed:
Thiamine triphosphate + H(2)O = thiamine diphosphate + phosphate
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thiamine-triphosphatase Chain: A
Molecule details ›
Chain: A
Length: 224 amino acids
Theoretical weight: 24.24 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8JZL3 (Residues: 2-224; Coverage: 100%)
Gene name: Thtpa
Sequence domains: CYTH domain
Structure domains: Hypothetical Protein Pfu-838710-001

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 88%
Refinement method: torsion angle dynamics,simulated annealing,distance geometry
Chemical shifts: BMR15063  
Expression system: Escherichia coli