PDBe 2j8j

Solution NMR

Solution Structure of the A4 Domain of Blood Coagulation Factor XI


Function and Biology Details

Reaction catalysed:
Selective cleavage of Arg-|-Ala and Arg-|-Val bonds in factor IX to form factor IXa.
Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Coagulation factor XIa heavy chain Chains: A, B
Molecule details ›
Chains: A, B
Length: 90 amino acids
Theoretical weight: 9.96 KDa
Source organism: Homo sapiens
  • Canonical: NEW P03951 (Residues: 290-379; Coverage: 15%)
Gene name: F11
Sequence domains: PAN domain
Structure domains: Hepatocyte Growth Factor

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: CNS