PDBe 2ifq

X-ray diffraction
1.2Å resolution

Crystal structure of S-nitroso thioredoxin

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Thioredoxin Chains: A, C
Molecule details ›
Chains: A, C
Length: 105 amino acids
Theoretical weight: 11.78 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P10599 (Residues: 1-105; Coverage: 100%)
Gene names: TRDX, TRX, TRX1, TXN
Sequence domains: Thioredoxin
Structure domains: Glutaredoxin
Thioredoxin Chain: B
Molecule details ›
Chain: B
Length: 105 amino acids
Theoretical weight: 11.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P10599 (Residues: 1-105; Coverage: 100%)
Gene names: TRDX, TRX, TRX1, TXN
Sequence domains: Thioredoxin
Structure domains: Glutaredoxin

Ligands and Environments

1 bound ligand:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 14-BM-C
Spacegroup: C2
Unit cell:
a: 116.08Å b: 25.749Å c: 85.86Å
α: 90° β: 97.97° γ: 90°
R-values:
R R work R free
0.179 0.177 0.206
Expression system: Escherichia coli