PDBe 2i5o

Solution NMR

Solution Structure of the Ubiquitin-Binding Zinc Finger (UBZ) Domain of the Human DNA Y-Polymerase Eta

Released:
Source organism: Homo sapiens

Function and Biology Details

Reaction catalysed:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA polymerase eta Chain: A
Molecule details ›
Chain: A
Length: 39 amino acids
Theoretical weight: 4.42 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9Y253 (Residues: 628-662; Coverage: 5%)
Gene names: POLH, RAD30, RAD30A, XPV
Sequence domains: Ubiquitin-Binding Zinc Finger

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 86%
Refinement method: Structure originally calculated by torsion angle dynamics and refined by water refinement.
Chemical shifts: BMR15160  
Expression system: Escherichia coli