PDBe 2hzq

X-ray diffraction
1.8Å resolution

Crystal structure of human apolipoprotein D (ApoD) in complex with progesterone

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Apolipoprotein D Chain: A
Molecule details ›
Chain: A
Length: 174 amino acids
Theoretical weight: 19.99 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P05090 (Residues: 23-189; Coverage: 99%)
Gene name: APOD
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

1 bound ligand:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P43212
Unit cell:
a: 49.206Å b: 49.206Å c: 144.126Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.189 0.187 0.226
Expression system: Escherichia coli