PDBe 2hn7

X-ray diffraction
1.6Å resolution

HLA-A*1101 in complex with HBV peptide homologue

Released:
Source organism: Homo sapiens
Primary publication:
Structure of HLA-A*1101 in complex with a hepatitis B peptide homologue.
Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 62 1179-84 (2006)
PMID: 17142892

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
HLA class I histocompatibility antigen, A-11 alpha chain Chain: A
Molecule details ›
Chain: A
Length: 275 amino acids
Theoretical weight: 31.86 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P13746 (Residues: 25-299; Coverage: 81%)
Gene names: HLA-A, HLAA
Sequence domains:
Structure domains:
Beta-2-microglobulin Chain: B
Molecule details ›
Chain: B
Length: 99 amino acids
Theoretical weight: 11.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P61769 (Residues: 21-119; Coverage: 100%)
Gene names: B2M, CDABP0092, HDCMA22P
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
DNA polymerase PEPTIDE HOMOLOGUE Chain: C
Molecule details ›
Chain: C
Length: 10 amino acids
Theoretical weight: 1.2 KDa

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: P21
Unit cell:
a: 58.023Å b: 79.664Å c: 56.319Å
α: 90° β: 116.4° γ: 90°
R-values:
R R work R free
0.508 0.148 0.212
Expression system: Escherichia coli BL21(DE3)