PDBe 2hbs

X-ray diffraction
2.05Å resolution

THE HIGH RESOLUTION CRYSTAL STRUCTURE OF DEOXYHEMOGLOBIN S

Released:
Source organism: Homo sapiens
Primary publication:
The high resolution crystal structure of deoxyhemoglobin S.
J. Mol. Biol. 272 398-407 (1997)
PMID: 9325099

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Hemoglobin subunit beta Chains: B, D, F, H
Molecule details ›
Chains: B, D, F, H
Length: 146 amino acids
Theoretical weight: 15.86 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P68871 (Residues: 2-147; Coverage: 99%)
Gene name: HBB
Sequence domains: Globin
Structure domains: Globins
Hemoglobin subunit alpha Chains: A, C, E, G
Molecule details ›
Chains: A, C, E, G
Length: 141 amino acids
Theoretical weight: 15.15 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P69905 (Residues: 2-142; Coverage: 99%)
Gene names: HBA1, HBA2
Sequence domains: Globin
Structure domains: Globins

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH2R
Spacegroup: P21
Unit cell:
a: 63.344Å b: 185.681Å c: 52.933Å
α: 90° β: 92.74° γ: 90°
R-values:
R R work R free
0.165 0.165 0.215