PDBe 2h7v

X-ray diffraction
2.6Å resolution

Co-crystal structure of YpkA-Rac1


Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ras-related C3 botulinum toxin substrate 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 188 amino acids
Theoretical weight: 20.79 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
  • Canonical: NEW P63000 (Residues: 1-184; Coverage: 96%)
Gene names: MIG5, RAC1, TC25
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases
Protein kinase YpkA Chains: C, D
Molecule details ›
Chains: C, D
Length: 303 amino acids
Theoretical weight: 34.45 KDa
Source organism: Yersinia pseudotuberculosis
Expression system: Escherichia coli BL21(DE3)
  • Canonical: NEW Q05608 (Residues: 434-732; Coverage: 41%)
Gene names: pYV0001, ypkA
Sequence domains: Rac1-binding domain
Structure domains:

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P1
Unit cell:
a: 66.398Å b: 75.519Å c: 99.772Å
α: 92.08° β: 103.38° γ: 115.79°
R R work R free
0.224 0.222 0.257
Expression system: Escherichia coli BL21(DE3)