PDBe 2h79

X-ray diffraction
1.87Å resolution

Crystal Structure of human TR alpha bound T3 in orthorhombic space group

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thyroid hormone receptor alpha Chain: A
Molecule details ›
Chain: A
Length: 269 amino acids
Theoretical weight: 31.08 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P10827 (Residues: 148-370; Coverage: 46%)
Gene names: EAR7, ERBA1, NR1A1, THRA, THRA1, THRA2
Structure domains: Retinoid X Receptor

Ligands and Environments

1 bound ligand:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P212121
Unit cell:
a: 59.981Å b: 80.795Å c: 102.211Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.15 0.149 0.187
Expression system: Escherichia coli