PDBe 2gox

X-ray diffraction
2.2Å resolution

Crystal structure of Efb-C / C3d Complex

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Complement C3d fragment Chains: A, C
Molecule details ›
Chains: A, C
Length: 297 amino acids
Theoretical weight: 33.14 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P01024 (Residues: 996-1287; Coverage: 18%)
Gene names: C3, CPAMD1
Structure domains: Glycosyltransferase
Fibrinogen-binding protein Chains: B, D
Molecule details ›
Chains: B, D
Length: 65 amino acids
Theoretical weight: 7.59 KDa
Source organism: Staphylococcus aureus subsp. aureus Mu50
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P68799 (Residues: 101-165; Coverage: 48%)
Gene names: SAV1158, efb, fib
Sequence domains: Extracellular fibrinogen binding protein C terminal
Structure domains: Arc Repressor Mutant, subunit A

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-BM
Spacegroup: P41
Unit cell:
a: 90.939Å b: 90.939Å c: 122.242Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.184 0.181 0.231
Expression system: Escherichia coli BL21(DE3)