PDBe 2gf7

X-ray diffraction
2.2Å resolution

Double tudor domain structure

Released:
Source organism: Homo sapiens

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lysine-specific demethylase 4A Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 119 amino acids
Theoretical weight: 13.47 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O75164 (Residues: 895-1011; Coverage: 11%)
Gene names: JHDM3A, JMJD2, JMJD2A, KDM4A, KIAA0677
Structure domains: SH3 type barrels.

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X26C
Spacegroup: R32
Unit cell:
a: 189.915Å b: 189.915Å c: 116.317Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.264 0.225 0.264
Expression system: Escherichia coli BL21(DE3)