PDBe 2fuf

X-ray diffraction
1.45Å resolution

Crystal structure of the SV40 large T antigen origin-binding domain

Released:

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Large T antigen Chain: A
Molecule details ›
Chain: A
Length: 134 amino acids
Theoretical weight: 15.51 KDa
Source organism: Macaca mulatta polyomavirus 1
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P03070 (Residues: 131-260; Coverage: 18%)
Sequence domains: Origin of replication binding protein
Structure domains: Replication Protein E1; Chain: A,

Ligands and Environments

1 bound ligand:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P65
Unit cell:
a: 83.669Å b: 83.669Å c: 35.88Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.17 0.169 0.189
Expression system: Escherichia coli BL21