PDBe 2frw

Solution NMR

Solution structure of the second SH3 domain of human adaptor protein NCK2

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cytoplasmic protein NCK2 Chain: A
Molecule details ›
Chain: A
Length: 57 amino acids
Theoretical weight: 6.57 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: O43639 (Residues: 114-170; Coverage: 15%)
Gene names: GRB4, NCK2
Sequence domains: Variant SH3 domain
Structure domains: SH3 Domains

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 57%
Refinement method: distance geometry, simulated annealing
Chemical shifts: BMR7035  
Expression system: Escherichia coli BL21