PDBe 2fjz

X-ray diffraction
1.61Å resolution

Structure of the Alzheimer's Amyloid Precursor Protein (APP) copper binding domain (residues 133 to 189) in 'small unit cell' form, metal-free

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
N-APP Chain: A
Molecule details ›
Chain: A
Length: 59 amino acids
Theoretical weight: 6.85 KDa
Source organism: Homo sapiens
Expression system: Komagataella pastoris
UniProt:
  • Canonical: P05067 (Residues: 133-189; Coverage: 8%)
Gene names: A4, AD1, APP
Structure domains: Amyloid beta a4 protein copper binding domain

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200H
Spacegroup: P212121
Unit cell:
a: 31.346Å b: 32.518Å c: 50.2Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.177 0.177 0.209
Expression system: Komagataella pastoris