PDBe 2fej

Solution NMR

Solution structure of human p53 DNA binding domain.

Released:
Source organism: Homo sapiens
Primary publication:
Solution structure of p53 core domain: structural basis for its instability.
Proc. Natl. Acad. Sci. U.S.A. 103 2109-14 (2006)
PMID: 16461916

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cellular tumor antigen p53 Chain: A
Molecule details ›
Chain: A
Length: 204 amino acids
Theoretical weight: 23.01 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P04637 (Residues: 94-297; Coverage: 52%)
Gene names: P53, TP53
Sequence domains: P53 DNA-binding domain
Structure domains: Immunoglobulin-like

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Escherichia coli