PDBe 2e2q

X-ray diffraction
2Å resolution

Crystal structure of Sulfolobus tokodaii hexokinase in complex with xylose, Mg2+, and ADP

Released:

Function and Biology Details

Reaction catalysed:
ATP + D-hexose = ADP + D-hexose 6-phosphate
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ATP-dependent hexokinase Chains: A, B
Molecule details ›
Chains: A, B
Length: 299 amino acids
Theoretical weight: 32.16 KDa
Source organism: Sulfolobus tokodaii
Expression system: Escherichia coli
UniProt:
  • Canonical: Q96Y14 (Residues: 1-299; Coverage: 100%)
Gene names: ST2354, STK_23540
Sequence domains: BadF/BadG/BcrA/BcrD ATPase family
Structure domains: Nucleotidyltransferase; domain 5

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-6A
Spacegroup: C2
Unit cell:
a: 143.44Å b: 81.47Å c: 52.51Å
α: 90° β: 109.4° γ: 90°
R-values:
R R work R free
0.213 0.213 0.255
Expression system: Escherichia coli