PDBe 2d39

X-ray diffraction
1.9Å resolution

Trivalent Recognition Unit of Innate Immunity System; Crystal Structure of human M-ficolin Fibrinogen-like Domain

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ficolin-1 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 237 amino acids
Theoretical weight: 26.86 KDa
Source organism: Homo sapiens
Expression system: Komagataella pastoris
UniProt:
  • Canonical: O00602 (Residues: 115-326; Coverage: 71%)
Gene names: FCN1, FCNM
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL24XU
Spacegroup: P21
Unit cell:
a: 55.16Å b: 117.45Å c: 55.19Å
α: 90° β: 99.88° γ: 90°
R-values:
R R work R free
0.209 0.209 0.24
Expression system: Komagataella pastoris