PDBe 2cr3

Solution NMR

Solution structure of the first Ig-like domain of human fibroblast growth factor receptor 1

Released:
Source organism: Homo sapiens
Entry authors: Hatta R, Hayashi F, Yoshida M, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fibroblast growth factor receptor 1 Chain: A
Molecule details ›
Chain: A
Length: 99 amino acids
Theoretical weight: 10.41 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P11362 (Residues: 38-123; Coverage: 11%)
Gene names: BFGFR, CEK, FGFBR, FGFR1, FLG, FLT2, HBGFR
Sequence domains: Immunoglobulin domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Not provided