PDBe 2cka

Solution NMR

Solution structures of the BRK domains of the human Chromo Helicase Domain 7 and 8, reveals structural similarity with GYF domain suggesting a role in protein interaction

Released:
Source organism: Homo sapiens
Entry authors: Ab E, de Jong RN, Diercks T, Xiaoyun J, Daniels M, Kaptein R, Folkers GE

Function and Biology Details

Reaction catalysed:
ATP + H(2)O = ADP + phosphate
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Chromodomain-helicase-DNA-binding protein 8 Chain: A
Molecule details ›
Chain: A
Length: 95 amino acids
Theoretical weight: 11.06 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9HCK8 (Residues: 2276-2286, 2287-2364; Coverage: 3%)
Gene names: CHD8, HELSNF1, KIAA1564
Sequence domains: BRK domain
Structure domains: Rubrerythrin, domain 2

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 88%
Refinement method: CANDID IN CYANA
Chemical shifts: BMR15098  
Expression system: Escherichia coli BL21(DE3)