PDBe 2ci8

X-ray diffraction
1.8Å resolution

sh2 domain of human nck1 adaptor protein - uncomplexed


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Cytoplasmic protein NCK1 Chain: A
Molecule details ›
Chain: A
Length: 99 amino acids
Theoretical weight: 11.51 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
  • Canonical: P16333 (Residues: 281-377; Coverage: 26%)
Gene names: NCK, NCK1
Sequence domains: SH2 domain
Structure domains:

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: C222
Unit cell:
a: 62.854Å b: 82.484Å c: 44.538Å
α: 90° β: 90° γ: 90°
R R work R free
0.232 0.23 0.274
Expression system: Escherichia coli BL21