PDBe 2ce9

X-ray diffraction
2.12Å resolution

A WRPW peptide bound to the Groucho-TLE WD40 domain.


Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Transducin-like enhancer protein 1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 337 amino acids
Theoretical weight: 36.85 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
  • Canonical: Q04724 (Residues: 436-770; Coverage: 44%)
Gene name: TLE1
Sequence domains: WD domain, G-beta repeat
Structure domains: YVTN repeat-like/Quinoprotein amine dehydrogenase
Molecule details ›
Chains: X, Y
Length: 5 amino acids
Theoretical weight: 776 Da
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: P21
Unit cell:
a: 107.81Å b: 56.478Å c: 126.642Å
α: 90° β: 112.68° γ: 90°
R R work R free
0.181 0.178 0.244
Expression systems:
  • Spodoptera frugiperda
  • Not provided