PDBe 2c63

X-ray diffraction
2.15Å resolution

14-3-3 Protein Eta (Human) Complexed to Peptide

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
14-3-3 protein eta Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 247 amino acids
Theoretical weight: 28.34 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q04917 (Residues: 1-246; Coverage: 100%)
Gene names: YWHA1, YWHAH
Sequence domains: 14-3-3 protein
Structure domains: 14-3-3 domain
CONSENSUS PEPTIDE FOR 14-3-3 PROTEINS Chains: P, Q, R, S
Molecule details ›
Chains: P, Q, R, S
Length: 6 amino acids
Theoretical weight: 737 Da
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

No bound ligands

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P21
Unit cell:
a: 58.251Å b: 79.398Å c: 125.109Å
α: 90° β: 95.15° γ: 90°
R-values:
R R work R free
0.185 0.184 0.248
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided