PDBe 2c10

X-ray diffraction
2.5Å resolution

The structure of a truncated, soluble version of semicarbazide- sensitive amine oxidase

Released:
Source organism: Homo sapiens
Primary publication:
Structure of human semicarbazide-sensitive amine oxidase/vascular adhesion protein-1.
Acta Crystallogr. D Biol. Crystallogr. 61 1550-62 (2005)
PMID: 16239734

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Membrane primary amine oxidase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 735 amino acids
Theoretical weight: 81.6 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q16853 (Residues: 29-763; Coverage: 96%)
Gene names: AOC3, VAP1
Sequence domains:
Structure domains:

Ligands and Environments

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: P43
Unit cell:
a: 130.236Å b: 130.236Å c: 221.529Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.204 0.204 0.252
Expression system: Homo sapiens