PDBe 2bss

X-ray diffraction
2Å resolution

Crystal structures and KIR3DL1 recognition of three immunodominant viral peptides complexed to HLA-B2705

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
HLA class I histocompatibility antigen, B-27 alpha chain Chain: A
Molecule details ›
Chain: A
Length: 276 amino acids
Theoretical weight: 31.93 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P03989 (Residues: 25-300; Coverage: 82%)
Gene names: HLA-B, HLAB
Sequence domains:
Structure domains:
Beta-2-microglobulin Chain: B
Molecule details ›
Chain: B
Length: 100 amino acids
Theoretical weight: 11.88 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P61769 (Residues: 21-119; Coverage: 100%)
Gene names: B2M, CDABP0092, HDCMA22P
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
Gag protein Chain: C
Molecule details ›
Chain: C
Length: 10 amino acids
Theoretical weight: 1.24 KDa
Source organism: Human immunodeficiency virus
Expression system: Not provided
UniProt:
  • Canonical: Q98Y46 (Residues: 2-11; Coverage: 53%)

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: P212121
Unit cell:
a: 51.3Å b: 82.4Å c: 108.5Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.231 0.231 not available
Expression systems:
  • Escherichia coli
  • Not provided