PDBe 2bp3

X-ray diffraction
2.32Å resolution

Crystal structure of Filamin A domain 17 and GPIb alpha cytoplasmic domain complex

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Filamin-A Chains: A, B
Molecule details ›
Chains: A, B
Length: 97 amino acids
Theoretical weight: 9.98 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P21333 (Residues: 1862-1956; Coverage: 4%)
Gene names: FLN, FLN1, FLNA
Sequence domains: Filamin/ABP280 repeat
Structure domains: Immunoglobulins
Platelet glycoprotein Ib alpha chain Chains: S, T
Molecule details ›
Chains: S, T
Length: 22 amino acids
Theoretical weight: 2.56 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P07359 (Residues: 598-619; Coverage: 4%)
Gene name: GP1BA

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P212121
Unit cell:
a: 41.9Å b: 62.8Å c: 122.8Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.216 0.214 0.256
Expression systems:
  • Escherichia coli BL21
  • Not provided