PDBe 2beg

Solution NMR

3D Structure of Alzheimer's Abeta(1-42) fibrils

Released:
Source organism: Homo sapiens
Primary publication:
3D structure of Alzheimer's amyloid-beta(1-42) fibrils.
Proc. Natl. Acad. Sci. U.S.A. 102 17342-7 (2005)
PMID: 16293696

Function and Biology Details

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Amyloid-beta protein 42 Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 42 amino acids
Theoretical weight: 4.52 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P05067 (Residues: 672-713; Coverage: 6%)
Gene names: A4, AD1, APP
Sequence domains: Beta-amyloid peptide (beta-APP)

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: Escherichia coli BL21(DE3)