PDBe 2bdj

X-ray diffraction
2.5Å resolution

Function and Biology Details

Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Proto-oncogene tyrosine-protein kinase Src Chain: A
Molecule details ›
Chain: A
Length: 279 amino acids
Theoretical weight: 31.97 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: NEW P12931 (Residues: 258-536; Coverage: 52%)
Gene names: SRC, SRC1
Sequence domains: Protein tyrosine kinase
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: P21
Unit cell:
a: 42.1Å b: 54.6Å c: 69Å
α: 90° β: 99.97° γ: 90°
R-values:
R R work R free
0.158 0.158 0.277
Expression system: Spodoptera frugiperda