PDBe 2b8t

X-ray diffraction
2Å resolution

Crystal structure of Thymidine Kinase from U.urealyticum in complex with thymidine

Released:

Function and Biology Details

Reaction catalysed:
ATP + thymidine = ADP + thymidine 5'-phosphate
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thymidine kinase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 223 amino acids
Theoretical weight: 25.44 KDa
Source organism: Ureaplasma parvum
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9PPP5 (Residues: 1-223; Coverage: 100%)
Gene names: UU594, tdk
Sequence domains: Thymidine kinase
Structure domains:

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-3
Spacegroup: P21
Unit cell:
a: 57.158Å b: 115.649Å c: 64.474Å
α: 90° β: 101.02° γ: 90°
R-values:
R R work R free
0.197 0.195 0.235
Expression system: Escherichia coli