PDBe 2b3y

X-ray diffraction
1.85Å resolution

Structure of a monoclinic crystal form of human cytosolic aconitase (IRP1)

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cytoplasmic aconitate hydratase Chains: A, B
Molecule details ›
Chains: A, B
Length: 888 amino acids
Theoretical weight: 98.37 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P21399 (Residues: 2-889; Coverage: 100%)
Gene names: ACO1, IREB1
Sequence domains:
Structure domains:

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4, ESRF BEAMLINE BM30A
Spacegroup: P21
Unit cell:
a: 63.91Å b: 215.47Å c: 64.01Å
α: 90° β: 72° γ: 90°
R-values:
R R work R free
0.213 0.211 0.261
Expression system: Escherichia coli