PDBe 2b3x

X-ray diffraction
2.54Å resolution

Structure of an orthorhombic crystal form of human cytosolic aconitase (IRP1)


Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Cytoplasmic aconitate hydratase Chain: A
Molecule details ›
Chain: A
Length: 888 amino acids
Theoretical weight: 98.37 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P21399 (Residues: 2-889; Coverage: 100%)
Gene names: ACO1, IREB1
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM30A
Spacegroup: C2221
Unit cell:
a: 75.352Å b: 103.307Å c: 225.957Å
α: 90° β: 90° γ: 90°
R R work R free
0.183 0.18 0.225
Expression system: Escherichia coli