Function and Biology Details
Structure analysis Details
Assembly composition:
hetero hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138137 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Replication protein A 70 kDa DNA-binding subunit, N-terminally processed
Molecule details ›
Chain: A
Length: 123 amino acids
Theoretical weight: 13.47 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Replication factor-A protein 1, N-terminal domain
Structure domains: Nucleic acid-binding proteins
Length: 123 amino acids
Theoretical weight: 13.47 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P27694 (Residues: 1-120; Coverage: 20%)
Sequence domains: Replication factor-A protein 1, N-terminal domain
Structure domains: Nucleic acid-binding proteins
Cellular tumor antigen p53
Molecule details ›
Chain: B
Length: 28 amino acids
Theoretical weight: 3.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Transactivation domain 2
Length: 28 amino acids
Theoretical weight: 3.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P04637 (Residues: 33-60; Coverage: 7%)
Sequence domains: Transactivation domain 2
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
RIGAKU RU300
Spacegroup:
P212121
Expression system: Escherichia coli BL21(DE3)
