PDBe 2af9

X-ray diffraction
2Å resolution

Crystal Structure analysis of GM2-Activator protein complexed with phosphatidylcholine

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ganglioside GM2 activator Chain: A
Molecule details ›
Chain: A
Length: 164 amino acids
Theoretical weight: 17.83 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P17900 (Residues: 32-193; Coverage: 95%)
Gene name: GM2A
Sequence domains: ML domain
Structure domains: Ganglioside GM2 activator

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P212121
Unit cell:
a: 39.12Å b: 41.98Å c: 114.21Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.222 0.222 0.279
Expression system: Escherichia coli BL21(DE3)