PDBe 2ado

X-ray diffraction
1.45Å resolution

Crystal Structure Of The Brct Repeat Region From The Mediator of DNA damage checkpoint protein 1, MDC1


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Mediator of DNA damage checkpoint protein 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 196 amino acids
Theoretical weight: 21.51 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q14676 (Residues: 1891-2086; Coverage: 9%)
Gene names: KIAA0170, MDC1, NFBD1
Structure domains: Rossmann fold

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.3.1
Spacegroup: P1
Unit cell:
a: 42.051Å b: 44.44Å c: 61.942Å
α: 72.95° β: 87.54° γ: 61.8°
R R work R free
0.195 0.195 0.212
Expression system: Escherichia coli