PDBe 2aaq

X-ray diffraction
2.6Å resolution

Crystal Structure Analysis of the human Glutahione Reductase, complexed with GoPI

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutathione reductase, mitochondrial Chain: A
Molecule details ›
Chain: A
Length: 479 amino acids
Theoretical weight: 51.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P00390 (Residues: 44-522; Coverage: 92%)
Gene names: GLUR, GRD1, GSR
Sequence domains:
Structure domains:

Ligands and Environments


Cofactor: Ligand FAD 1 x FAD

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: C2
Unit cell:
a: 120.31Å b: 62.72Å c: 83.99Å
α: 90° β: 122.47° γ: 90°
R-values:
R R work R free
0.201 0.201 0.259
Expression system: Escherichia coli